The Advanced Center for the Detection of Cancer (ACDC) Laboratory conducts basic and translational biomedical research focused on understanding disease mechanisms and supporting the development of improved methods for disease detection, monitoring, and therapeutic research. The laboratory’s activities have historically emphasized cancer research, while also encompassing other areas of human disease biology.

Research efforts integrate molecular biology, proteomics, genomics, immunology, and mass spectrometry to investigate biological pathways relevant to disease development and progression. Studies are carried out using cell-based systems, biological samples, and experimental models, with an emphasis on generating reproducible and clinically relevant data.

A central theme of the laboratory’s work has been the discovery and validation of biomarkers, particularly proteins and molecular signatures detectable in biological fluids and tissues. These investigations support research into early disease detection, disease classification, and translational applications, without making clinical or diagnostic claims.

The laboratory has maintained access to biorepositories of biological fluids, tissues, and nucleic acids, enabling large-scale studies and collaboration with clinical and academic partners. Research projects have been conducted in collaboration with investigators from universities, hospitals, and research institutes worldwide, reflecting a multidisciplinary and international approach.

This overview is provided for educational and informational purposes and summarizes publicly documented research themes associated with the ACDC Laboratory over time.

Primary Research Themes

• Cancer biology and biomarker discovery
• Proteomics and mass spectrometry–based analysis
• Translational biomedical research
• Molecular mechanisms of carcinogenesis and disease progression
• Research into neurodegenerative, autoimmune, and reproductive disorders

Research Approach

• Integration of basic and translational research
• Use of high-throughput and analytical technologies
• Collaboration across clinical and research disciplines
• Emphasis on reproducibility and methodological rigor